Personalized Blends: Offers multiple targeted formulas based on your cognitive goals and responses, allowing a more customized experience. Influencer Backing: Strong support from well-known figures like Andrew Huberman adds a layer of credibility and public trust.

Limited Clinical Validation: While Thesis has expressed plans for future trials, current scientific evidence behind its custom blends is still emerging. Higher Cost: Personalized stacks come at a premium, making it more expensive than many traditional nootropic supplements. Subjective Results: Much of the feedback driving personalization is based on self-reports, which can vary in accuracy. Low Ingredient Dosages: Several components fall below clinically effective doses, which may limit their potential impact.

Alpha GPC, a choline-based compound, supports acetylcholine production—a neurotransmitter vital for learning and memory. Research shows Alpha GPC can boost memory, focus, and cognitive function, particularly in neurological conditions like dementia [3][4]. It’s safe, well-tolerated, and commonly used in both supplements and medical settings. Thesis Clarity includes 500 mg, which is among the higher doses seen in nootropic products. While it has demonstrated benefits in clinical populations, more evidence is needed to confirm its effects in healthy adults.

Citicoline is frequently studied for its memory-supporting properties, particularly for episodic memory—the ability to recall personal events. Clinical research suggests that 500 mg daily can improve memory and cognitive performance in healthy individuals [16][17]. Thesis Energy includes 300 mg, which is below the dose most studies associate with measurable benefits.

Rich in mangiferin, mango leaf extract has shown anti-inflammatory and antioxidant properties, along with potential neuroprotective effects. Animal studies link it to reduced brain inflammation, protection against bleeding, and improved cognition [18][19][20]. It’s also explored for mitigating complications of metabolic disorders (like type 2 diabetes) that raise dementia risks. Thesis Energy provides 300 mg, but human trials confirming its cognitive benefits remain limited.

Theacrine, a purine alkaloid similar to caffeine, is found in the Camellia kucha plant. Studies report it can boost energy, focus, and cognitive performance, with less habituation compared to caffeine [21]. Research in athletes suggests benefits for reaction time and endurance, either on its own or combined with caffeine [22][23]. Thesis Energy contains 100 mg, a relatively low amount compared to doses often used in studies, so effects may be milder.

An amino acid that helps boost dopamine levels, L-Tyrosine supports cognitive flexibility and performance during stress or high mental demand. Research indicates its effects are most noticeable when neurotransmitter activity is briefly depleted (e.g., stress or fatigue) [29][30]. Optimal doses for cognitive benefits typically start at 2 grams, well above the 300 mg included in Thesis Energy. While potentially helpful under specific conditions, the dose here is significantly below what research suggests for measurable impact.

Alpha GPC, a choline-based compound, supports acetylcholine production—a neurotransmitter vital for learning and memory. Research shows Alpha GPC can boost memory, focus, and cognitive function, particularly in neurological conditions like dementia [3][4]. It’s safe, well-tolerated, and commonly used in both supplements and medical settings. Thesis Clarity includes 500 mg, which is among the higher doses seen in nootropic products. While it has demonstrated benefits in clinical populations, more evidence is needed to confirm its effects in healthy adults.

Agmatine acts as a neuromodulator within the central nervous system, but so far, research has been limited to animal studies. Findings suggest potential antidepressant and anti-anxiety effects, likely due to its impact on nitric oxide pathways and its ability to reduce oxidative stress while boosting BDNF levels [31][32]. It’s been shown to be safe in rodents, with oral doses increasing brain concentrations, but human research is lacking. Thesis Creativity uses 250 mg, while rodent studies used significantly higher doses (15–600 mg per kg), making the human efficacy uncertain.

Panax ginseng, found here at 200 mg, is well-studied for its adaptogenic and brain-supportive properties. It helps the body manage stress, boosts mental and physical resilience, and can improve memory—especially in cases of age-related cognitive decline [33][34][35]. Standard supplemental doses range from 200 mg of extract to 0.5–2 g of dry root. It’s generally safe but should be used cautiously in those with acute asthma or hypertension, as high doses can overstimulate and raise blood pressure.

Ashwagandha is a traditional herb with evidence supporting its benefits for stress reduction, oxidative stress management, and cognitive health. Animal research links it to improved aerobic capacity, lower oxidative damage, and potential benefits in conditions like tardive dyskinesia and Alzheimer’s [36][37][38]. Effective doses range from 6–10 g ground root or 100–1250 mg of extract daily [39][40]. Thesis Creativity provides 300 mg, which falls within the recommended range for cognitive and stress-relief benefits.

An essential amino acid, L-Phenylalanine has been researched for its potential to improve mood and attention, particularly in conditions like ADHD and depression. Studies suggest up to 1200 mg daily can temporarily enhance mood and focus in ADHD, though tolerance often develops within 2–4 months [44]. In depressed patients, 75–200 mg/day for 20 days improved symptoms in 12 of 20 participants [45]. It’s also been used in treatments for depression, arthritis, and addiction recovery [46]. Thesis Motivation includes 500 mg, which could offer some benefit, but its impact on motivation specifically is less certain.

A purine alkaloid, Methylliberine is often paired with caffeine to support energy, motivation, and focus. Research shows it can boost concentration and mood without significantly affecting heart rate or blood pressure [47]. It’s been explored for enhancing mental performance in scenarios like gaming or tactical settings [48][49]. The 100 mg dose in Thesis Motivation matches amounts used in current studies, suggesting it may deliver mild cognitive and mood-enhancing effects.

Traditionally used in herbal medicine, saffron has shown potential for improving cognitive function in people with Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI). Some studies suggest its effects may be on par with standard drugs for these conditions, without adding side effects [59][60]. However, most available research carries a high risk of bias, so more rigorous trials are needed before drawing strong conclusions. Most studies use 30 mg daily, while Thesis Confidence includes 28 mg, just shy of the typical dose.

Sage (Salvia) is traditionally associated with memory enhancement. A single study found that sage oil ingestion improved immediate word recall in healthy young adults, potentially due to its effects on acetylcholinesterase activity [65]. However, these findings haven’t been widely replicated, and its broader cognitive impact remains uncertain. Thesis Confidence uses 333 mg, but sage remains one of the more speculative inclusions across the blends.

Magnolia officinalis is a traditional remedy for anxiety and mood disorders. In rodent studies, ethanol extracts improved cognitive function, lowered stress-induced hormone spikes, and reduced anxiety-like behavior [66]. Its primary active compound, honokiol, interacts with GABA and CB1 receptors, suggesting potential neuroprotective and mood-regulating benefits [67]. All supporting data is from animal studies, so its 10 mg dose in Thesis Confidence is theoretical and unverified for humans.

Extracted from the leaves and fruit of the Ginkgo tree, this ingredient is rich in antioxidants, supports circulation, and offers anti-inflammatory properties. Animal studies show it can help with chronic brain issues by influencing inflammatory pathways and the cholinergic system [68]. Human trials indicate benefits for working memory and processing speed [69], though its effectiveness in healthy adults under 60 is debated [70]. Typical doses range from 120–300 mg daily. Side effects are rare but may include mild stomach upset, headaches, or blood thinning (a concern for those on anticoagulants). Thesis Logic contains 160 mg, falling within the standard dosage range.

Theobromine, a compound naturally found in chocolate, may offer neuroprotective effects over time. Research suggests it could help reduce Alzheimer’s-related pathology but has a weaker immediate cognitive effect compared to caffeine [71]. Its influence on mood and alertness appears inconsistent, as nutritionally relevant doses don’t always show measurable benefits [72]. When combined with caffeine, theobromine may deliver some cognitive and mood benefits without raising blood pressure [73]. Thesis Logic provides 100 mg, though most studies suggest doses over 400 mg are needed for noticeable cognitive impact.

A key phospholipid in brain cell membranes, phosphatidylserine is vital for healthy neurotransmission and cognitive function. Studies show it can support memory, focus, and learning, particularly as the brain ages [74][75]. It’s well-absorbed, crosses the blood-brain barrier, and is generally well-tolerated. Typical effective doses range from 100–800 mg per day [76][77]. With 400 mg per serving, Thesis Logic includes a dose that aligns with the levels used in studies for cognitive support.

DHA is a crucial omega-3 fatty acid for brain health, supporting neuronal membranes and cognitive performance. Evidence shows DHA, especially when paired with EPA, can enhance memory and cognitive ability, particularly in older adults with mild memory decline [78]. Most benefits are seen at 1 g or more per day, often in combination with EPA. Thesis Logic contains 200 mg, which is far below typical levels associated with cognitive benefits.

Triacetyluridine has primarily been researched as a potential treatment for bipolar depression. In a study with eleven participants, doses up to 18 g daily over six weeks significantly reduced depressive symptoms and improved mitochondrial function [79]. While promising, these doses are vastly higher than what’s included here. Thesis Logic offers just 30 mg, far below any clinically studied amount.

A well-researched herbal extract, Bacopa supports memory, learning, and overall cognitive performance. Its bacosides (A and B) are linked to enhanced memory formation, recall, and neuroprotection [80]. Clinical studies in older adults show improvements in mood, attention, and cognitive ability, though more research is needed to confirm broader benefits [81][82][83]. Effective daily doses typically range from 200–400 mg. Thesis Logic contains 320 mg, placing it within the proven range for cognitive enhancement.

My Experience Taking Thesis Nootropics (2025 Review)

Thesis has carved a unique niche in the wellness space with its personalized nootropic formulas, tailored to fit an individual’s specific cognitive profile. Endorsements from high-profile names in the health world have propelled its visibility—sparking curiosity and a surge in interest.

But does Thesis actually deliver on its promises?

Pros

Personalized Blends: Offers multiple targeted formulas based on your cognitive goals and responses, allowing a more customized experience.
Influencer Backing: Strong support from well-known figures like Andrew Huberman adds a layer of credibility and public trust.

Cons

Limited Clinical Validation: While Thesis has expressed plans for future trials, current scientific evidence behind its custom blends is still emerging.
Higher Cost: Personalized stacks come at a premium, making it more expensive than many traditional nootropic supplements.
Subjective Results: Much of the feedback driving personalization is based on self-reports, which can vary in accuracy.
Low Ingredient Dosages: Several components fall below clinically effective doses, which may limit their potential impact.

Quick Verdict

Thesis is an effective nootropic supplement for smooth energy and no crashes. But there are better formulas for the price.

Our #1 nootropic of choice is Mind Lab Pro. It’s formulated with an effective stack of nootropic ingredients without any stimulants so you can take it any time of day to improve cognitive function in the short and long term.

CHECK CURRENT MIND LAB PRO DEALS

CHECK CURRENT THESIS DEALS

What Are Thesis Nootropics?

Thesis Nootropics is a brand focused on delivering personalized cognitive enhancement supplements. Founded by Dan Freed in 2017, the company was born from his own struggles with focus and attention—challenges he eventually overcame through the use of nootropics.

That personal transformation sparked the vision behind Thesis: helping others discover their ideal nootropic blend through a tailored, test-based approach.

Rather than offering a one-size-fits-all formula, Thesis encourages users to try different targeted blends to see what works best for their unique brain chemistry.

The brand’s growth has been largely fueled by personalization, word-of-mouth, and high-profile endorsements from figures like Dr. Andrew Huberman, Rich Roll, Kevin Love, and Kate Bock. Backed by over $13.5 million in funding, Thesis is continuing to expand and is reportedly operating profitably.

Thesis Nootropic Ingredients

Thesis offers six targeted blends designed to enhance different aspects of mental performance. Each formula can be customized with or without caffeine and L-Theanine. This duo is widely regarded as one of the most effective quick-acting nootropic stacks, improving reaction time, visual processing, memory, alertness, and reducing fatigue [1][2].

Most studies use a 2:1 ratio of L-Theanine to caffeine, which Thesis follows. Since this combination is standard across all blends, the focus below is on the unique ingredients in the Clarity Blend.

Thesis Clarity Blend

Alpha GPC

Alpha GPC, a choline-based compound, supports acetylcholine production—a neurotransmitter vital for learning and memory.

Research shows Alpha GPC can boost memory, focus, and cognitive function, particularly in neurological conditions like dementia [3][4].
It’s safe, well-tolerated, and commonly used in both supplements and medical settings.
Thesis Clarity includes 500 mg, which is among the higher doses seen in nootropic products.

While it has demonstrated benefits in clinical populations, more evidence is needed to confirm its effects in healthy adults.

Lion’s Mane Mushroom

Lion’s Mane (Hericium erinaceus) contains compounds that stimulate nerve growth factor (NGF), which supports nerve cell growth and brain regeneration [7].

Studies link it to improved memory, mood, and potential benefits for cognitive decline [8][9][10].
The mushroom’s primary effects stem from boosting NGF, indirectly supporting brain health rather than directly enhancing cognition [11].

Thesis Clarity uses 500 mg, which may contribute to long-term cognitive support. The focus is on the fruiting body (not mycelium), where most active compounds are concentrated.

Camellia Sinensis Tea Leaf

Camellia Sinensis, the plant behind tea, shows different neurological effects depending on the part used.

Seed extracts appear to enhance energy and mood, while leaf extracts tend to have a calming, mood-balancing effect.
Most data comes from animal studies [12], and there’s little to no human research to establish effective doses.

Thesis Clarity contains 278 mg of the tea leaf extract, though its nootropic potential remains mostly theoretical.

Dihydroxyflavone (7,8-DHF)

7,8-Dihydroxyflavone acts as a TrkB receptor agonist, mimicking the activity of brain-derived neurotrophic factor (BDNF), which supports neuron survival and brain adaptability.

In rodent studies, it has been shown to enhance learning, memory formation, and spatial recall—even improving outcomes in Alzheimer’s models [13][14][15].
It also mitigates age-related memory issues in animal models by boosting synaptic plasticity.

While promising, all research so far is in animals, so its relevance to humans remains uncertain.

Thesis Energy Blend Ingredients

Citicoline

Citicoline is frequently studied for its memory-supporting properties, particularly for episodic memory—the ability to recall personal events.

Clinical research suggests that 500 mg daily can improve memory and cognitive performance in healthy individuals [16][17].
Thesis Energy includes 300 mg, which is below the dose most studies associate with measurable benefits.

Mango Leaf

Rich in mangiferin, mango leaf extract has shown anti-inflammatory and antioxidant properties, along with potential neuroprotective effects.

Animal studies link it to reduced brain inflammation, protection against bleeding, and improved cognition [18][19][20].
It’s also explored for mitigating complications of metabolic disorders (like type 2 diabetes) that raise dementia risks.

Thesis Energy provides 300 mg, but human trials confirming its cognitive benefits remain limited.

Theacrine

Theacrine, a purine alkaloid similar to caffeine, is found in the Camellia kucha plant.

Studies report it can boost energy, focus, and cognitive performance, with less habituation compared to caffeine [21].
Research in athletes suggests benefits for reaction time and endurance, either on its own or combined with caffeine [22][23].

Thesis Energy contains 100 mg, a relatively low amount compared to doses often used in studies, so effects may be milder.

N-Acetyl Cysteine (NAC)

NAC is studied for its antioxidant and anti-inflammatory properties, with potential benefits for brain health and disorders like psychosis, bipolar disorder, and Alzheimer’s disease.

Some trials show improvements in working memory for psychosis patients [24], though results for bipolar disorder remain inconclusive [25].
Human studies typically use 600–2000 mg daily for cognitive outcomes [26][27].

Thesis Energy contains 500 mg, which may fall short of the range used in most research.

Indian Trumpet Tree (Oroxylum Indicum)

In the only available human study, older adults with memory issues took 500 mg twice daily for 12 weeks.

Participants showed better episodic and numeric working memory, along with faster learning in location-based tasks [28].
However, no improvements were seen across broader cognitive measures, and more studies are needed to confirm its potential.

Thesis Energy uses 100 mg, far below the studied dose, making benefits less likely.

L-Tyrosine

An amino acid that helps boost dopamine levels, L-Tyrosine supports cognitive flexibility and performance during stress or high mental demand.

Research indicates its effects are most noticeable when neurotransmitter activity is briefly depleted (e.g., stress or fatigue) [29][30].
Optimal doses for cognitive benefits typically start at 2 grams, well above the 300 mg included in Thesis Energy.

While potentially helpful under specific conditions, the dose here is significantly below what research suggests for measurable impact.

Thesis Creativity Blend Ingredients

Alpha GPC

This blend includes 150 mg of Alpha GPC, significantly less than the 500 mg found in Thesis Clarity.

Alpha GPC supports acetylcholine production, a neurotransmitter crucial for memory and learning.
Clinical studies suggest doses closer to 500 mg are more effective for boosting cognitive performance, so the smaller dose here may limit its benefits.

Agmatine Sulfate

Agmatine acts as a neuromodulator within the central nervous system, but so far, research has been limited to animal studies.

Findings suggest potential antidepressant and anti-anxiety effects, likely due to its impact on nitric oxide pathways and its ability to reduce oxidative stress while boosting BDNF levels [31][32].
It’s been shown to be safe in rodents, with oral doses increasing brain concentrations, but human research is lacking.

Thesis Creativity uses 250 mg, while rodent studies used significantly higher doses (15–600 mg per kg), making the human efficacy uncertain.

Panax Ginseng

Panax ginseng, found here at 200 mg, is well-studied for its adaptogenic and brain-supportive properties.

It helps the body manage stress, boosts mental and physical resilience, and can improve memory—especially in cases of age-related cognitive decline [33][34][35].
Standard supplemental doses range from 200 mg of extract to 0.5–2 g of dry root.
It’s generally safe but should be used cautiously in those with acute asthma or hypertension, as high doses can overstimulate and raise blood pressure.

Ashwagandha Root

Ashwagandha is a traditional herb with evidence supporting its benefits for stress reduction, oxidative stress management, and cognitive health.

Animal research links it to improved aerobic capacity, lower oxidative damage, and potential benefits in conditions like tardive dyskinesia and Alzheimer’s [36][37][38].
Effective doses range from 6–10 g ground root or 100–1250 mg of extract daily [39][40].

Thesis Creativity provides 300 mg, which falls within the recommended range for cognitive and stress-relief benefits.

Sceletium Tortuosum (Kanna)

Known for its mood-enhancing and calming effects, Sceletium Tortuosum is also being explored for its neuroprotective potential.

Early research suggests benefits for conditions like Alzheimer’s and Parkinson’s through antioxidant effects and receptor interactions [41][42].
It’s most recognized for reducing anxiety and depression while promoting relaxation and overall well-being [43].

Thesis Creativity contains 25 mg, which matches doses used in human studies.

Thesis Motivation Blend Ingredients

L-Phenylalanine

An essential amino acid, L-Phenylalanine has been researched for its potential to improve mood and attention, particularly in conditions like ADHD and depression.

Studies suggest up to 1200 mg daily can temporarily enhance mood and focus in ADHD, though tolerance often develops within 2–4 months [44].
In depressed patients, 75–200 mg/day for 20 days improved symptoms in 12 of 20 participants [45].
It’s also been used in treatments for depression, arthritis, and addiction recovery [46].

Thesis Motivation includes 500 mg, which could offer some benefit, but its impact on motivation specifically is less certain.

Methylliberine

A purine alkaloid, Methylliberine is often paired with caffeine to support energy, motivation, and focus.

Research shows it can boost concentration and mood without significantly affecting heart rate or blood pressure [47].
It’s been explored for enhancing mental performance in scenarios like gaming or tactical settings [48][49].

The 100 mg dose in Thesis Motivation matches amounts used in current studies, suggesting it may deliver mild cognitive and mood-enhancing effects.

Vitamin B12 (Speculative)

B12 is vital for brain health, but supplementation primarily benefits those who are deficient.

Low B12 levels are linked to cognitive decline and conditions like Alzheimer’s and Parkinson’s [50].
However, evidence is weak for benefits in people with normal B12 status [51].
B12 may influence brain volume and function, but more research is needed to confirm its nootropic potential [52].

Thesis Motivation contains 1000 mcg, which is unlikely to enhance cognition unless you’re deficient.

Forskolin (Speculative)

Derived from Coleus forskohlii, forskolin shows promise in animal research for supporting brain health.

In rodent studies, it improved memory, reduced Alzheimer’s-like symptoms, and regulated brain inflammation [53][54].
It’s also demonstrated protective effects against Huntington’s-like neurodegeneration by reducing oxidative stress and improving learning [55].

Thesis Motivation delivers 250 mg, but given that all findings are in animals, its real-world cognitive benefits remain unproven.

Artichoke (Speculative)

Artichoke extract has been noted for its prebiotic and antioxidant properties, with potential cognitive benefits.

In mice, it promoted gut health, which can indirectly support cognition [56].
In elderly adults with mild cognitive impairment, artichoke paired with aerobic exercise improved cognitive status and reduced insulin resistance [57].
Certain varieties, like Romanesco Siciliano, show notable antioxidant power, which could help protect brain health [58].

Thesis Motivation includes 450 mg, far below the amounts used in these studies, making noticeable effects unlikely.

Thesis Confidence Blend Ingredients

Saffron

Traditionally used in herbal medicine, saffron has shown potential for improving cognitive function in people with Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI).

Some studies suggest its effects may be on par with standard drugs for these conditions, without adding side effects [59][60].
However, most available research carries a high risk of bias, so more rigorous trials are needed before drawing strong conclusions.

Most studies use 30 mg daily, while Thesis Confidence includes 28 mg, just shy of the typical dose.

Magnesium Bisglycinate

Magnesium plays a vital role in brain health and has been linked to benefits for memory and cognition in healthy adults.

It appears effective at boosting brain magnesium levels and may help with depression symptoms, though findings are mixed across different mental health conditions [61][62][63][64].
While 500 mg (as found in this blend) can help correct deficiencies, there’s little evidence that it directly improves confidence or mood in non-deficient individuals.

Sage

Sage (Salvia) is traditionally associated with memory enhancement.

A single study found that sage oil ingestion improved immediate word recall in healthy young adults, potentially due to its effects on acetylcholinesterase activity [65].
However, these findings haven’t been widely replicated, and its broader cognitive impact remains uncertain.

Thesis Confidence uses 333 mg, but sage remains one of the more speculative inclusions across the blends.

Sceletium Tortuosum

Also featured in the Creativity Blend, Sceletium Tortuosum (Kanna) is known for its calming, mood-enhancing properties.

The 25 mg dose used here aligns with amounts tested in human trials.

Magnolia Bark

Magnolia officinalis is a traditional remedy for anxiety and mood disorders.

In rodent studies, ethanol extracts improved cognitive function, lowered stress-induced hormone spikes, and reduced anxiety-like behavior [66].
Its primary active compound, honokiol, interacts with GABA and CB1 receptors, suggesting potential neuroprotective and mood-regulating benefits [67].

All supporting data is from animal studies, so its 10 mg dose in Thesis Confidence is theoretical and unverified for humans.

Ashwagandha Leaf & Root

This blend includes 120 mg of a mix of ashwagandha root and leaf.

Ashwagandha extracts (typically 100–1200 mg) are associated with stress reduction and cognitive benefits, as discussed in the Creativity Blend section.
The root is where most of the active compounds are concentrated, so a mixed root-and-leaf dose may be less potent overall.

Thesis Logic Blend Ingredients

Ginkgo Biloba

Extracted from the leaves and fruit of the Ginkgo tree, this ingredient is rich in antioxidants, supports circulation, and offers anti-inflammatory properties.

Animal studies show it can help with chronic brain issues by influencing inflammatory pathways and the cholinergic system [68].
Human trials indicate benefits for working memory and processing speed [69], though its effectiveness in healthy adults under 60 is debated [70].
Typical doses range from 120–300 mg daily. Side effects are rare but may include mild stomach upset, headaches, or blood thinning (a concern for those on anticoagulants).

Thesis Logic contains 160 mg, falling within the standard dosage range.

Theobromine

Theobromine, a compound naturally found in chocolate, may offer neuroprotective effects over time.

Research suggests it could help reduce Alzheimer’s-related pathology but has a weaker immediate cognitive effect compared to caffeine [71].
Its influence on mood and alertness appears inconsistent, as nutritionally relevant doses don’t always show measurable benefits [72].
When combined with caffeine, theobromine may deliver some cognitive and mood benefits without raising blood pressure [73].

Thesis Logic provides 100 mg, though most studies suggest doses over 400 mg are needed for noticeable cognitive impact.

Phosphatidylserine

A key phospholipid in brain cell membranes, phosphatidylserine is vital for healthy neurotransmission and cognitive function.

Studies show it can support memory, focus, and learning, particularly as the brain ages [74][75].
It’s well-absorbed, crosses the blood-brain barrier, and is generally well-tolerated.
Typical effective doses range from 100–800 mg per day [76][77].

With 400 mg per serving, Thesis Logic includes a dose that aligns with the levels used in studies for cognitive support.

High DHA Algae

DHA is a crucial omega-3 fatty acid for brain health, supporting neuronal membranes and cognitive performance.

Evidence shows DHA, especially when paired with EPA, can enhance memory and cognitive ability, particularly in older adults with mild memory decline [78].
Most benefits are seen at 1 g or more per day, often in combination with EPA.

Thesis Logic contains 200 mg, which is far below typical levels associated with cognitive benefits.

Triacetyluridine

Triacetyluridine has primarily been researched as a potential treatment for bipolar depression.

In a study with eleven participants, doses up to 18 g daily over six weeks significantly reduced depressive symptoms and improved mitochondrial function [79].
While promising, these doses are vastly higher than what’s included here.

Thesis Logic offers just 30 mg, far below any clinically studied amount.

Bacopa Monnieri

A well-researched herbal extract, Bacopa supports memory, learning, and overall cognitive performance.

Its bacosides (A and B) are linked to enhanced memory formation, recall, and neuroprotection [80].
Clinical studies in older adults show improvements in mood, attention, and cognitive ability, though more research is needed to confirm broader benefits [81][82][83].
Effective daily doses typically range from 200–400 mg.

Thesis Logic contains 320 mg, placing it within the proven range for cognitive enhancement.

Thesis Nootropics Price

Thesis offers two ways to purchase its nootropic blends: a one-time purchase or a subscription plan. Pricing is structured as follows:

Subscription: $79
One-Time Purchase: $119

These prices apply whether you order the personalized starter kit or build your own box.

Individual blends aren’t sold separately—you’re required to purchase four boxes at a time. For custom orders, you can choose four of the same blend or mix and match different options.

The starter kit is designed so you can try each blend for one week (each container holds a week’s supply) to determine which works best for you.

By incorporating personalization and mandatory multi-box purchases, Thesis has positioned itself as one of the most expensive nootropic options on the market.

Is Thesis Nootropics Really Personalized?

I took the initial quiz to see how Thesis builds its “personalized” nootropic stack.

Here’s what they recommended for me:

It’s clear the personalization is more about marketing than true customization. Creating fully unique formulations for every individual just isn’t realistic.

That said, having multiple blends does let you experiment to find which ones work best for your needs.

If you select the caffeine options, every blend will feel effective to some degree. The issue is that many of the other ingredients are speculative, often backed only by animal research, and several are underdosed.

Benefits Of Thesis Nootropics

Multiple Blends For Different Purposes

This is marketed as a major advantage, but in reality, it mostly comes down to preference. Some people may feel certain blends fit them better than others, so it does give flexibility within a single brand.

Thesis also claims the ingredients in each formula work synergistically. There’s no research supporting this, but at least there’s no evidence of negative interactions either.

Options For Stimulants Or Not

You can choose blends with or without stimulants. If you go with the caffeine and L-theanine stack, which is one of the most proven combinations for boosting focus and alertness, all of the blends will likely provide noticeable effects.

If you’re already a heavy coffee drinker or plan on using Thesis later in the day, choosing stimulant-free options is the smarter choice.

My Experience With Thesis

Based on my quiz, I was recommended the Clarity, Logic, Motivation, and Confidence Blends. I tested each for a week without caffeine, since adding the caffeine and L-theanine stack tends to make any blend work.

The Confidence and Motivation Blends didn’t do much for me. I didn’t notice any significant brain-boosting effects, nor did I feel more confident or motivated.

The Logic and Clarity Blends, however, gave me small but noticeable improvements in focus when tackling mentally demanding work like writing, coaching, and podcasting.

If I were to keep using Thesis, those would be the two blends I’d stick with.

Who Is Thesis For?

Busy Working Professionals

Thesis Nootropics cater to professionals who deal with long work hours and high-stress demands. These blends are designed to improve focus, decision-making, and overall productivity while maintaining steady mental energy throughout the day, helping you tackle heavy workloads without burning out.

Creative Artists

For artists and creatives, Thesis offers blends aimed at boosting divergent thinking and breaking through mental roadblocks. They can help sustain periods of creative flow and support fresh, innovative perspectives during extended creative sessions.

Students

Thesis can be a useful tool for students, especially during exam periods or when juggling demanding academic projects. The blends are formulated to help with concentration, memory retention, and learning efficiency, making it easier to process and recall large amounts of information.

Gamers

Gamers looking to gain a performance edge may find Thesis helpful. These blends can support faster reaction times, improved focus, and sharper strategic thinking during long or competitive sessions, keeping you alert and engaged.

Coffee Haters

For those who don’t enjoy coffee or want to avoid caffeine-induced jitters, Thesis provides a non-coffee alternative to boost alertness and mental energy. This is especially useful for people sensitive to caffeine or looking to cut back without losing focus.

User Testimonials And Reviews

Thesis doesn’t have a public review database on its website, so I looked elsewhere for feedback. Here are two user reviews I found:

“I must admit that during the weeks that I consistently take them, I perform better & I generally feel better just knowing I’ve ingested something intended to positively alter my natural brain state. Minor tasks/chores no longer seem as daunting and I get this underlying kick to complete my work well.”

“I didn’t find Weeks 1 and 4 to do anything for me, but Weeks 2 and 3 really helped avoid the post-lunch, post-work slumps I tend to get now that I’ve been working from home; Energy is especially useful for days when I haven’t gotten enough sleep the night before.”

I couldn’t find many negative reviews aside from mentions of occasional migraines, which can occur for a variety of reasons and may not be directly related to the blends.

Thesis Side Effects

Side effects appear to be rare with these blends. I didn’t experience any while testing the four formulas, but as with any supplement, side effects are possible.

Consult a healthcare professional before using Thesis, especially if you’re pregnant, breastfeeding, have a medical condition, or take prescription medications.

Thesis Alternatives

If Thesis Nootropics doesn’t feel like the right fit or you’re looking to compare options, here are several alternatives I’ve personally tried and can speak on.

Nooceptin

Nooceptin by SAP Nutra is a stimulant-free nootropic designed for steady improvements in memory, focus, and overall brain function.

It offers a gradual boost without the energy spikes or crashes associated with caffeine, making it suitable for students, professionals, gamers, and older adults.

Its formula includes Lion’s Mane Extract, Citicoline, Rhodiola Rosea, L-Theanine, Bacopa Monnieri, Ginkgo Biloba, and Panax Ginseng. Some of these ingredients are backed by research, while others are more experimental.

Effects typically start to show within 7 to 14 days. While some components may be underdosed and the product sits at a higher price point, Nooceptin can be a solid stimulant-free option for long-term cognitive support.

Mind Lab Pro

Mind Lab Pro is one of the most widely recognized nootropics on the market, formulated with 11 research-supported ingredients aimed at improving clarity, focus, and mental energy.

It’s stimulant-free, making it a good choice for those who want a comprehensive daily brain supplement without caffeine.

The blend supports a range of cognitive functions, including memory, mood, attention, and processing speed. While some critics point out that a few ingredients could use higher doses or more clinical validation, Mind Lab Pro remains a top choice for students, professionals, athletes, and older adults looking for balanced brain support.

Our Mind Lab Pro review breaks it down in full detail.

NooCube

NooCube has become a popular nootropic for its ability to enhance cognition without stimulants.

It features ingredients like Bacopa Monnieri, L-Tyrosine, and L-Theanine, which are known for supporting mental performance, though others such as Huperzine-A and Alpha GPC still require more research to fully validate their benefits.

With its transparent labeling and caffeine-free design, NooCube appeals to professionals, students, older adults, gamers, and even combat athletes who want cognitive support without jitters.

You can find our in-depth analysis in the NooCube review.

Frequently Asked Thesis Questions

What Is Thesis Nootropic And What Does It Do?

Thesis Nootropic is a supplement line offering different blends aimed at improving cognitive functions. Depending on the blend, benefits may include better focus, reduced procrastination, improved stress management, and enhanced memory recall.

Does Thesis Work Like Adderall?

While both are used to boost cognitive performance, Thesis Nootropics and Adderall work very differently.
Adderall is a prescription medication for ADHD and narcolepsy, classified as an amphetamine and a controlled substance due to its strong stimulant effects and potential for dependence.

Thesis Nootropics, on the other hand, are dietary supplements designed for generally healthy individuals looking to enhance focus, memory, and mental clarity. They are not meant to treat medical conditions like ADHD.

How Long Does It Take Thesis Nootropics To Work?

If you’re using a blend with caffeine, effects can be felt within about 30 minutes. Non-stimulant blends may also start to work quickly but tend to feel subtler and can sometimes take several weeks to deliver noticeable benefits.

Final Thoughts

After testing multiple blends, it’s clear that Thesis’s “personalization” is more marketing than true customization. That said, the variety of blends does allow for some experimentation, which may help you find a formula that works best for your needs.