5 Best NMN Supplements in 2024

In the ever-evolving world of dietary supplements, Nicotinamide Mononucleotide (NMN) has emerged as a frontrunner for those seeking enhanced health and longevity. NMN supplements have gained popularity for their role in boosting NAD+ levels, a critical coenzyme in cellular energy metabolism and aging processes.

Today, there is a variety of NMN supplements, each claiming unique benefits. This article provides an in-depth analysis of the top NMN supplements, evaluating their features, efficacy, customer reviews, and overall value to help you make an informed decision. It is important to understand that you want to purchase a product containing Nicotinamie Riboside, which allows for better absorption.

1. Thorne Niacel® 400 NMN

Thorne Niacel 400 emerges as a standout NMN supplement with a perfect 5/5-star rating and a price of $51 for 60 servings when you sign up under Athletic Insight. This high-grade supplement is specifically formulated to counteract early signs of aging and boost daily vitality by replenishing NAD+ levels. It features a potent blend of 415mg Nicotinamide Riboside and 85mg Betaine Anhydrous per capsule, combined with other ingredients like Calcium Laurate, Hypromellose Capsule, Microcrystalline Cellulose, and Silicon Dioxide for optimal absorption and efficacy.

Thorne Niacel® 400 NMN
Thorne Niacel® 400 NMN

Targeting the modern lifestyle challenges that contribute to NAD+ depletion, such as lack of sleep, prolonged desk work, and unbalanced diets, NiaCel 400 is engineered to support cellular health at its core. The inclusion of Nicotinamide Riboside, a precursor to NAD+, is instrumental in enhancing cellular energy production and supporting a normal sleep-wake cycle. The added Betaine Anhydrous not only promotes optimal methylation for healthy detox processes and balanced brain chemicals but also aids in supporting lean body composition by reducing body fat without affecting muscle mass.

The long-term benefits of NiaCel 400 are significant, making it a choice supplement for healthy aging. It boosts NAD+ production to combat chronological aging, supports healthy cellular repair and metabolism, promotes cellular energy production, aids in weight management, and protects DNA from damage. This additional support for NAD+ makes NiaCel 400 ideal for athletes and individuals requiring robust support for depleted NAD+ levels.

2. Reus Research NMN Supplement Alternative

The Reus Research NMN Supplement Alternative stands out with its innovative formulation and high value. This supplement offers a unique combination of Liposomal Nicotinamide Riboside, Astragalus, Resveratrol, and Quercetin, specifically designed to enhance anti-aging efforts, boost energy levels, and sharpen focus. Each package contains 80 capsules, providing a generous 40 servings.

Reus Research NMN Supplement Alternative
Reus Research NMN Supplement Alternative

Reus Research NMN alternative is distinguished by its ability to increase NAD levels by 63%, leveraging the synergistic effects of its components. Liposomal Nicotinamide Riboside, a direct substitute for NMN supplements, works efficiently in the body to enhance NAD precursor absorption, offering noticeable anti-aging benefits. The inclusion of Astragalus, Resveratrol, and Quercetin not only supports longevity but also contributes to overall vitality and well-being.

Manufactured and rigorously third-party tested in the USA, the Reus Research NMN Supplement Alternative guarantees purity and effectiveness, with certificates of quality available upon request. Its cutting-edge Liposomal Nicotinamide Riboside encapsulation technology ensures an impressive 71% increase in absorption, making it significantly more effective than other supplements with different delivery methods.

Recommended at a dosage of 2 capsules per day, this supplement promises to restore a sense of youthfulness and vigor. Its 4.6/5 star rating is a testament to its efficacy in delivering a potent blend that supports healthy aging, energy production, focus, and longevity. The Reus Research NMN Supplement Alternative not only represents a leap in supplement technology but also offers exceptional value and efficacy for those seeking to combat the signs of aging and enhance their daily vitality.

3. Renue By Science NAD⁺ Complete

Renue By Science NAD⁺ Complete, priced at $84.95 for 90 capsules, is a trailblazer in the field of NAD+ supplementation. Designed for optimal efficacy, the supplement requires a dosage of 2 capsules per day and employs cutting-edge liposomal delivery technology to maximize the potency of NAD+, NMN, and NR. This innovative approach ensures that the body absorbs these key nutrients more effectively than traditional oral capsules.

Renue By Science NAD⁺ Complete
Renue By Science NAD⁺ Complete

Understanding the complexity of NAD⁺ pathways in the body, Renue By Science has developed a three-in-one capsule, encompassing all three precursors to target different tissues and maximize the restoration of NAD⁺ levels throughout the body. This comprehensive formulation is underpinned by the belief that addressing all pathways is crucial for effective NAD⁺ replenishment.

The cornerstone of Renue By Science NAD⁺ Complete is its liposomal encapsulation of active ingredients. Liposomes are tiny phospholipid bubbles that encapsulate and protect the nutrients, delivering them directly to cells via the bloodstream. This revolutionary method overcomes the common challenges of nutrient degradation in the stomach and poor absorption in the small intestine, issues that typically plague traditional supplements.

Liposomal delivery ensures not only targeted absorption but also a delayed-release effect, leading to prolonged circulation of nutrients in the bloodstream and significantly enhanced bioavailability. The higher bioavailability directly translates to a more potent effect on the body. The supplement’s liposomal capsules are designed to maximize the effects of key ingredients, ensuring they reach the target tissues intact and potent.

Renue By Science NAD⁺ Complete, with its innovative liposomal delivery system, stands out as a comprehensive and effective solution for those seeking to boost their NAD⁺ levels. The supplement not only offers a sophisticated approach to NAD⁺ restoration but also represents a significant advancement in nutrient delivery technology, making it a top choice for individuals looking to enhance their cellular health and vitality


TRU NIAGEN, with a 4.4/5 star rating, offers an impactful NMN supplement priced at around $80 for 60 servings (120 capsules). It features 150mg of patented Nicotinamide Riboside (NR) per serving, designed to enhance cellular health and promote healthy aging. TRU NIAGEN’s commitment to quality is evident in its FDA notifications for safety and purity. Each batch undergoes rigorous testing in the United States, ensuring the highest standards.

Rooted in over two decades of scientific research, TRU NIAGEN is backed by 40+ patents and 300+ studies, making it a leader in NAD+ boosting supplements. It stands out for its efficiency in increasing NAD+ levels, vital for cellular function, particularly as the body ages. Regular use of TRU NIAGEN is clinically proven to elevate NAD+ levels by 40-50% over 8 weeks, supporting vital organs and overall vitality.

Users of TRU NIAGEN can expect noticeable improvements in health and well-being, with varying experiences based on individual needs. Its efficacy in raising NAD+ levels surpasses other NAD+ precursors, thanks to the superior absorption and utilization of its key ingredient, Niagen.

5. ProHealth NMN Pro 1000

ProHealth NMN Pro 1000 is a high-strength NMN supplement designed to combat aging and enhance overall health. It offers a substantial dose of 1000mg of Nicotinamide Mononucleotide (NMN) per serving, targeting key areas like heart health, muscle strength, and cognitive function. This supplement is particularly noted for its effectiveness in improving physical endurance and glucose metabolism, making it suitable for individuals experiencing age-related metabolic changes.

One of the primary benefits of NMN Pro 1000 is its ability to support longevity, as studies suggest that increasing NAD+ synthesis can extend lifespan in various organisms. It also plays a significant role in regulating blood sugar levels, which tend to rise with age. By enhancing skeletal muscle glucose metabolism, it helps in managing metabolic disorders. Additionally, NMN Pro 1000 contributes to maintaining a healthy weight by boosting NAD+ and ATP production, essential for an efficient metabolism.

With a focus on cognitive health, NMN Pro 1000 addresses the decline in cognitive function associated with aging by replenishing NAD+ stores. This support extends to skin health as well, where boosting NAD+ levels can prevent premature skin aging and promote a healthier appearance. Overall, ProHealth NMN Pro 1000 stands out as an effective solution for those seeking a comprehensive NMN supplement to address various aspects of aging and health maintenance.

What are NMN Supplements?

NMN (Nicotinamide Mononucleotide) supplements are designed to enhance the body’s levels of nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme in cellular metabolism. NMN is a direct precursor to NAD+, meaning it contributes to the synthesis of this vital molecule. With aging, NAD+ levels naturally decline, leading to decreased cellular function and vitality. By supplementing with NMN, the aim is to support and rejuvenate cellular processes, potentially offering anti-aging benefits and improved overall health. NMN supplements are generally regarded as safe, with ongoing research to further elucidate their long-term effects.

How to Choose an NMN Supplement?

When selecting an NMN supplement, it’s important to consider factors like purity, potency, and the credibility of the brand. Look for products that provide clear information on NMN content per serving and have undergone third-party testing for quality assurance. Additionally, consider the form of the supplement – whether in capsules, powders, or lozenges – as this can affect absorption and convenience of use. Compatibility with individual health conditions and potential interactions with medications should also be evaluated.

What to Look for When Buying NMN?

In purchasing NMN supplements, key aspects to consider include the dosage of NMN per serving, the presence of additional synergistic ingredients like resveratrol, and the manufacturing standards of the brand. It’s also wise to assess user reviews and clinical evidence supporting the product’s efficacy. Ensuring that the supplement does not contain unnecessary fillers or artificial additives is also crucial for safety and effectiveness.

What is the Most Popular NMN Supplement?

The most popular NMN supplement as of 2024 is often considered to be TRU NIAGEN due to its widespread recognition, clinical backing, and positive user testimonials. Its popularity stems from the brand’s commitment to research and transparency, as well as its moderate pricing, making it accessible to a wide range of consumers seeking the benefits of increased NAD+ levels.

What is the Cheapest NMN Supplement?

In terms of affordability, the cheapest NMN supplement on the market tends to fluctuate based on brand promotions and package deals. However, generic brands often offer lower-priced options, with some products available under $30. While cost is a consideration, it’s important to balance affordability with quality and efficacy.

What is the Most Expensive NMN Supplement?

On the higher end of the price spectrum, ProHealth NMN Pro 1000 stands out due to its high dosage and premium formulation. Its price point, around $100 for a month’s supply, reflects its targeted approach towards individuals seeking maximal NMN potency and rapid results.

What is the Best NMN Supplement with Resveratrol?

The combination of NMN with resveratrol is sought after for its synergistic effects in enhancing NAD+ levels and providing antioxidant benefits. Supplements like ‘Renue By Science NAD⁺ Complete’ stand out in this category, offering both NMN and resveratrol in a single formulation, optimizing the potential anti-aging and health-promoting effects.

What is the Best-Rated NMN Supplement?

As for the best-rated NMN supplement, Thorne Niacel consistently receives high marks for its effectiveness, quality, and reliability. Its positive ratings are supported by a strong base of scientific research and satisfied customer reviews, highlighting its impact on energy levels, cognitive function, and overall well-being.

How do NMN Supplements Work?

NMN supplements work by increasing the levels of NAD+ in the body. NAD+, or nicotinamide adenine dinucleotide, is a vital coenzyme found in all living cells and is crucial for energy production, DNA repair, and cell signaling. As we age, NAD+ levels naturally decline, leading to reduced cellular vitality and increased susceptibility to age-related diseases. By supplementing with NMN, which is a precursor to NAD+, the body can more effectively produce and maintain higher levels of NAD+, potentially counteracting some aging processes and supporting overall cellular health.

Does NMN Work Without Resveratrol?

Yes, NMN can be effective without resveratrol. While resveratrol, a natural polyphenol, is often combined with NMN for its synergistic effects on enhancing NAD+ levels and providing antioxidant benefits, NMN alone is still effective in boosting NAD+. NMN directly participates in the biosynthesis of NAD+, thus independently contributing to increased NAD+ levels and associated health benefits.

What is the Effect of NMN Supplements on the Body?

NMN supplements have several positive effects on the body, primarily through boosting NAD+ levels. They can improve energy metabolism, enhance DNA repair, and support cellular functions, potentially leading to benefits like increased energy, improved cognitive function, and slower aging processes. However, it’s important to note that individual responses to NMN can vary. While generally well-tolerated, some individuals might experience mild side effects like digestive discomfort or headaches, especially at higher doses.

How does NMN Supplement Affect the Metabolism?

NMN supplements positively influence metabolism by enhancing mitochondrial function, the powerhouse of the cell. By increasing NAD+ levels, NMN improves the efficiency of energy production in cells, potentially leading to higher metabolic rates, improved energy levels, and better management of body weight and composition.

Are NMN Supplements Effective in Boosting NAD+ Levels?

Yes, NMN supplements are effective in boosting NAD+ levels. Numerous studies and user experiences indicate that NMN supplementation can significantly increase NAD+ concentrations in the body, thereby supporting various cellular functions that rely on this vital coenzyme.

Are NMN Supplements Used for Anti-Aging?

Yes, one of the primary uses of NMN supplements is for their potential anti-aging benefits. By boosting NAD+ levels, NMN supplements are believed to support mechanisms that combat age-related cellular decline, including improving mitochondrial function, enhancing DNA repair, and reducing oxidative stress, which are all key factors in the aging process.

Who Can Take NMN Supplements?

NMN supplements are generally suitable for adults looking to support their cellular health and mitigate age-related decline. They are particularly beneficial for middle-aged and older adults, where NAD+ levels naturally decrease. However, individuals with certain health conditions or those on specific medications should consult a healthcare provider before starting NMN supplementation.

When to Take NMN Supplements?

The best time to take NMN supplements can vary depending on individual routines and preferences. Some studies suggest taking NMN in the morning may be more beneficial due to its potential effects on metabolism and energy levels. The recommended dosage typically ranges from 250 to 500 mg per day, but it can vary based on individual needs and the specific supplement formulation.

How Long Does it Take to See Results from NMN Supplements?

The timeframe for observing noticeable results from NMN supplementation can vary. Some individuals report feeling increased energy and improved cognitive function within a few weeks, while others may notice more gradual changes over several months. Consistency in supplementation is key for achieving optimal results.

Where to Buy NMN Supplements?

NMN supplements are widely available online through various retailers, including specialty health websites and larger platforms like Amazon. They can also be found in select health food stores and pharmacies. When purchasing NMN supplements, it’s important to buy from reputable sources to ensure product quality and authenticity.

Can the NMN Supplement be Shipped Globally?

Yes, many NMN supplement brands offer global shipping options. However, availability and shipping policies can vary based on the manufacturer and the destination country. It’s advisable to check with the specific brand or retailer for international shipping details and potential restrictions.

Can You Buy NMN Supplements Over the Counter?

While NMN supplements are not typically available over the counter in traditional pharmacies, they can be purchased without a prescription online and in some health food stores. As dietary supplements, they are more readily accessible compared to prescription medications.

What are the Alternatives to NMN Supplements?

Alternatives to NMN supplements for boosting NAD+ levels include nicotinamide riboside (NR) supplements and lifestyle changes like regular exercise and calorie restriction, both of which have been shown to naturally increase NAD+ levels. Other nutritional supplements like resveratrol and sirtuin activators can also complement NMN’s effects in promoting cellular health and longevity.

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Athletic Insight Research


The Athletic Insight Research team consists of a dedicated team of researchers, Doctors, Registered Dieticians, nationally certified nutritionists and personal trainers. Our team members hold prestigious accolades within their discipline(s) of expertise, as well as nationally recognized certifications. These include; National Academy of Sports Medicine Certified Personal Trainer (NASM-CPT), American College of Sports Medicine (ACSM), National Strength and Conditioning Association (NSCA-CPT), National Academy of Sports Medicine Certified Nutrition Coach (NASM-CNC), International Sports Sciences Association Nutritionist Certification.